I+D | Hitec

R&D

Department dedicated to the development, integration and implementation of different technologies for non-invasive measurement in real time.

History

Our R&D department was formally opened in 2007, as a leverage of our development and innovation policies which Hitec was implementing throughout the years, since its foundation more than 20 years ago. From the very beginning, R&D area had been focused to basic and applied research of a diverse set of topcs related to industry. It had been done through advanced technology instruments and actively building strong relationships with leading research institutions in industry and academia.

Nowadays, R&D department is mainly focused in development and deployment of different types of technologies related to non invasive in line real time measurements.

Mission

R&D works oriented keeping in mind the following mission:

Desing new products to solve our customer needs.
Develop innovative technical competencies to improve current control and measurement methods within productive processes quality parameters.
Active collaboration in between departments to deploy tools which offer best solutions to our customer concerns.
Foster knowledge and technology transfer through building strong relationships with other companies and academic institutions.

Primary Research Topics

VIS/NIR Spectrometry: In Line and On Line variable measurements such as moisture, proteins, particle size, fat, and many others.
Turbidimetry: On Line and In Line variable measurements such as solids, API content uniformity, and many others.
Ozone: On Line and In Line measurements of dissolved ozone in gas and liquid states in the context of UPW (Ultra Pure Water) and Water Wastewater.
Process simulations: Software development for process simulations abroad different industries such as Pharma, BioTec, Wastewater and many others.

International Published Papers

Muzzio, C.R., Dini, N.G., Díaz, R.J. In-line measurement of sunflower oil color in the Lovibond scale using a low-cost robust device. 2014. Journal of Food Engineering, 120, 88–93 / Elsevier
Díaz, R.J., Fernández Otero, G.C., Muzzio, C.R. Practical Application of Quality Risk Management to the Filling Process of Betamethasone Injections. 2011. Pharmaceutical Engineering, 31 (4) / ISPE
Muzzio, C.R., Dini, N.G. Simulation of freezing step in vial lyophilization using finite element method. 2011. Computers & Chemical Engineering, 35, 2274-2283 / Elsevier
Muzzio, C.R., Dini, N.G, Simionato, L.D. Determination of moisture content in lyophilized mannitol through intact glass vials using NIR micro-spectrometers. 2011. Brazilian Journal of Pharmaceutical Sciences, 47 (2), 289-297 / Brazilian Society of Chemical Engineering.
Cristian R. Muzzio, Martín A. Tomé, Rodolfo J. Díaz, Germán C.Fernández Otero, Pablo C. Campiutti, Héctor L. Cuevas, Nicolás G. Dini. In-line non-invasive turbidimetry as a tool to ensure content uniformity in the betamethasone filling process. 2015. International Journal of Pharmaceutics, In Press /